Brand Name	Generic Name
Actoplus Met (AK-toh-pluhss)(met)	pioglitazone (py-oh-GLIH-tuh-zohn) + metformin (met-FOR-min)

What does this type of pill do?

Actoplus Met is a combination of two types of pills. One pill lowers the amount of glucose made by your liver. Both types help your insulin work the way it should.

To learn more about the types of pills in Actoplus Met, see

• Insert J for information about pioglitazone (a thiazolidinedione)
• Insert E for information about metformin (a biguanide)

Brand Name	Generic Name
Avandamet (uh-VAN-duh-met)	rosiglitazone (rohss-ih-GLIH-tuh-zohn) + metformin (met-FOR-min)

What does this type of pill do?

Avandamet is a combination of two types of pills. One pill lowers the amount of glucose made by your liver. Both types help your insulin work the way it should.

To learn more about the types of pills in Avandamet, see

• Insert J for information about rosiglitazone (a thiazolidinedione)
• Insert E for information about metformin (a biguanide)

Brand Name	Generic Name
Avandaryl (uh-VAN-duh-ril)	rosiglitazone (rohss-ih-GLIH-tuh-zohn) + glimepiride (gly-MEP-ih-ryd)

What does this type of pill do?

Avandaryl is a combination of two types of pills. One pill helps your insulin work the way it should. The other pill helps your body make more insulin.

To learn more about the types of pills in Avandaryl, see

• Insert J for information about rosiglitazone (a thiazolidinedione)
• Insert I for information about glimepiride (a sulfonylurea)

Brand Name	Generic Name
Duetact (DOO-uh-tak)	pioglitazone (py-oh-GLIH-tuh-zohn) + glimepiride (gly-MEP-ih-ryd)

What does this type of pill do?

Duetact is a combination of two types of pills. One pill helps your insulin work the way it should. The other pill helps your body make more insulin.

To learn more about the types of pills in Duetact, see

• Insert J for information about pioglitazone (a thiazolidinedione)
• Insert I for information about glimepiride (a sulfonylurea)

Brand Names	Generic Name
Eucreas and Galvumet	vildagliptin (VILL-duh-GLIP-tin) + metformin (met-FOR-min)

What does this type of pill do?

Eucreas and Galvumet are a combination of two types of pills. One pill helps your body make more insulin when it's needed, especially right after meals. It also helps keep your liver from putting stored glucose into your blood. The other pill lowers the amount of glucose made by your liver and helps your insulin work the way it should.

To learn more about the types of pills in Eucreas/Galvumet, see

• Insert G for information about vildagliptin (a DPP-4 inhibitor)
• Insert E for information about metformin (a biguanide)

This product is not available in the United States or Japan. It is available in the UK, Australia, and probably elsewhere. [As of March, 2014]

Brand Name	Generic Name
Glucovance (GLOO-koh-vanss)	glyburide (GLY-buh-ryd) + metformin (met-FOR-min)

What does this type of pill do?

Glucovance is a combination of two types of pills. One pill helps your body make more insulin. The other pill lowers the amount of glucose made by your liver and helps your insulin work the way it should.

To learn more about the types of pills in Glucovance, see

• Insert I for information about glyburide (a sulfonylurea)
• Insert E for information about metformin (a biguanide)

Brand Name	Generic Name
Glyxambi	empagliflozin and linagliptin

What does this type of pill do?

Glyxambi is a combination of two types of pills. One pill works by blocking the reabsorption of glucose by the kidney, increasing glucose excretion, and the other pill lowers your blood glucose by helping your body make more insulin when it's needed, especially right after meals.

To learn more about the types of pills in Glyxambi, see

• Insert P for information about empagliflozin (an SGLT-2 Inhibitor)
• Insert G for information about linagliptin (a DPP-4 Inhibitor)

Brand Name	Generic Name
Invokamet	canagliflozin + metformin

What does this type of pill do?

Invokamet is a combination of two types of pills. One pill works by blocking the reabsorption of glucose by the kidney, increasing glucose excretion, and lowering blood glucose levels in diabetics who have elevated blood glucose levels. The other pill lowers the amount of glucose made by your liver and helps your insulin work the way it should.

To learn more about the types of pills in Invokamet, see

• Insert P for information about canagliflozin (an SGLT-2 Inhibitor)
• Insert E for information about metformin (a biguanide)

Brand Name	Generic Name
Janumet (JAN-yoo-met) and Janumet XR	sitagliptin (sih-tuh-GLIP-tin) + metformin (met-FOR-min)

What does this type of pill do?

Janumet is a combination of two types of pills. One pill helps your body make more insulin when it's needed, especially right after meals. It also helps keep your liver from putting stored glucose into your blood. The other pill lowers the amount of glucose made by your liver and helps your insulin work the way it should.

Janumet XR is an extended-release, once-daily formulation of Janumet.

To learn more about the types of pills in Janumet, see

• Insert G for information about sitagliptin (a DPP-4 inhibitor)
• Insert E for information about metformin (a biguanide)

For more information about Janumet/Janumet XR, see FDA Approves JANUMET® XR (sitagliptin and metformin HCl extended-release) for Type 2 Diabetes, Offering the Powerful Efficacy of JANUMET® (sitagliptin/metformin HCl) Now Available with Once-Daily Convenience (02Feb2012)

Brand Name	Generic Name
Kazano	alogliptin (AL-low-glip-tin) + metformin (met-FOR-min)

What does this type of pill do?

Kazano is a combination of two types of pills. One pill helps your body make more insulin when it's needed, especially right after meals. It also helps keep your liver from putting stored glucose into your blood. The other pill lowers the amount of glucose made by your liver and helps your insulin work the way it should.

To learn more about the types of pills in Kazano, see

• Insert G for information about alogliptin (a DPP-4 inhibitor)
• Insert E for information about metformin (a biguanide)

For more information about Kazano, see FDA approves three new drug treatments for type 2 diabetes (25Jan2013)

Brand Name	Generic Name
Kombiglyze	saxagliptin (sax-ah-glip-tin) + metformin (met-FOR-min)

What does this type of pill do?

Kazano is a combination of two types of pills. One pill helps your body make more insulin when it's needed, especially right after meals. It also helps keep your liver from putting stored glucose into your blood. The other pill lowers the amount of glucose made by your liver and helps your insulin work the way it should.

To learn more about the types of pills in Kombiglyze, see

• Insert G for information about saxagliptin (a DPP-4 inhibitor)
• Insert E for information about metformin (a biguanide)

Brand Name	Generic Name
Metaglip (MET-uh-glip)	glipizide (GLIP-ih-zyd) + metformin (met-FOR-min)

What does this type of pill do?

Metaglip is a combination of two types of pills. One pill helps your body make more insulin. The other pill lowers the amount of glucose made by your liver and helps your insulin work the way it should.

To learn more about the types of pills in Metaglip, see

• Insert I for information about glipizide (a sulfonylurea)
• Insert E for information about metformin (a biguanide)

Brand Name	Generic Name
Jentadueto	linagliptin (linn-ah-GLIP-tin) + metformin (met-FOR-min)

What does this type of pill do?

Jentadueto is a combination of two types of pills. One pill helps your body make more insulin when it's needed, especially right after meals. It also helps keep your liver from putting stored glucose into your blood. The other pill lowers the amount of glucose made by your liver and helps your insulin work the way it should.

To learn more about the types of pills in Jentadueto, see

• Insert G for information about linagliptin (a DPP-4 inhibitor)
• Insert E for information about metformin (a biguanide)

For more information about Jentadueto, see FDA approves Jentadueto™ (linagliptin/metformin hydrochloride) tablets for the treatment of adult patients with type 2 diabetes (30Jan2012)

Brand Name	Generic Name
Juvisync	sitagliptin (sit-ah-GLIP-tin) + simvastatin (sim-VAH-stat-inn)

What does this type of pill do?

Juvisync is a combination of two types of pills. One pill helps your body make more insulin when it's needed, especially right after meals. It also helps keep your liver from putting stored glucose into your blood. The other pill works to lowers the level of cholesterol.

To learn more about the types of pills in Juvisync, see

• Insert G for information about sitagliptin (a DPP-4 inhibitor)
• Simvastatin for information about simvastatin (a HMG-CoA reductase inhibitor, or "statin").

For more information about Juvisync, see FDA approves combination therapy Juvisync (07Oct2011)

Brand Name	Generic Name
Oseni	pioglitazone (py-oh-GLIH-tuh-zohn) + alogliptin

What does this type of pill do?

Oseni is a combination of two types of pills. One pill helps your body make more insulin when it's needed, especially right after meals. It also helps keep your liver from putting stored glucose into your blood. The other pill lowers the amount of glucose made by your liver. Both types help your insulin work the way it should.

To learn more about the types of pills in Oseni, see

• Insert G for information about alogliptin (a DPP-4 inhibitor)
• Insert J for information about pioglitazone (a thiazolidinedione)

Brand Name	Generic Name
Prandimet	rapaglinide (ruh-PAG-luh-nyd) + metformin (met-FOR-min)

What does this type of pill do?

Prandimet is a combination of two types of pills. One pill helps your body make more insulin for a short period of time right after meals. The insulin helps keep your blood glucose from going too high after you eat. The other pill lowers the amount of glucose made by your liver and helps your insulin work the way it should.

To learn more about the types of pills in Prandimet, see

• Insert H for information about rapaglinide (a meglitinide)
• Insert E for information about metformin (a biguanide)

Return to general information or go to Insert L