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Diabetes Information

Amaryl, Daonil, DiaBeta, Diabinese, Glucotrol, Glucotrol XL, Glynase PresTab, Micronase, tolazamide, and tolbutamide (Sulfonylureas)

Insert I

Brand Name Generic Name
Amaryl (AM-uh-ril) glimepiride (gly-MEP-ih-ryd)
Daonil (DAY-oh-nil)* glibenclamide (glib-EN-clam-IDE)
glyburide (gly-MEP-ih-ryd)**
DiaBeta (dy-uh-BAY-tuh) glibenclamide (glib-EN-clam-IDE)
glyburide (gly-MEP-ih-ryd)**
Diabinese (dy-AB-ih-neez) chlorpropamide (klor-PROH-puh-myd)
Glucotrol (GLOO-kuh-trohl) glipizide (GLIP-ih-zyd)
Glucotrol XL (GLOO-kuh-trohl)(EKS-EL) glipizide (GLIP-ih-zyd) (long-acting)
Glynase (GLY-nayz) PresTab glibenclamide (glib-EN-clam-IDE)
glyburide (gly-MEP-ih-ryd)**
Micronase (MY-kroh-nayz) glibenclamide (glib-EN-clam-IDE)
glyburide (gly-MEP-ih-ryd)**
Available only in generic form
tolazamide (tahl-AZ-uh-myd)
Available only in generic form
tolbutamide (tahl-BYOO-tuh-myd)

*   Daonil is not marketed in the United States.
** The term "glibenclamide" is frequently used outside the US, and "glyburide" in the US.

What does this type of pill do?

This type of pill helps your body make more insulin. The insulin helps lower your blood glucose.

Who should not take sulfonylureas?

Talk with your doctor about whether to take this type of pill if

  • you are allergic to sulfa drugs
  • you are pregnant, planning to get pregnant, or breastfeeding

What are the possible side effects?

Possible side effects include

  • low blood glucose, also called hypoglycemia (HY-poh-gly-SEE-mee-uh)-for more information, see Insert N
  • upset stomach
  • skin rash
  • weight gain
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Return to general information or go to Insert J

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Modified from the NDIC
NIH Publication No. 11-4222
October 2010


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