Return to the home page of DisforDiabetes




Diabetes Information

Epidemiology of Diabetes Interventions and Complications Study (EDIC)

On this page:

You can search for more information about


What Is EDIC?

The Epidemiology of Diabetes Interventions and Complications Study (EDIC) is an observational study examining the risk factors associated with the long-term complications of type 1 diabetes. The study began in 1994 and follows the 1441 participants previously enrolled in the Diabetes Control and Complications Trial (DCCT).

        go to the top of this page

EDIC Background

The Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Study is entering its 21st year. From 1983 to 1989, 1441 type 1 diabetic participants were recruited into the DCCT. They were randomly assigned to 2 treatment groups, intensive and conventional for an average of 6.5 years of randomized treatment time. The DCCT ended in 1993 after demonstrating conclusively that intensive treatment (mean HbA1c 7.2%) reduced the development and progression of diabetic retinopathy, nephropathy and neuropathy, compared to conventional treatment (mean HbA1c 9.0%).In 1994, 96% of the participants were enrolled in EDIC for regular observational follow-up of metabolic and complications status, using similar methods as in the DCCT. Diabetes care is obtained from the EDIC participants' own physicians.

        go to the top of this page

EDIC Objectives

The primary aim of EDIC is to examine the long-term effects of conventional vs. intensive diabetes treatment received during the DCCT on the subsequent development and progression of microvascular, neuropathic and cardiovascular complications. This involves studying the influence of genetic factors and other factors such as HbA1c, blood pressure, lipid levels, and treatment modalities on the development and progression of these complications.

        go to the top of this page

EDIC Clinical Centers

EDIC is made up of 28 clinical centers and one data coordinating center funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

Rockville, MD

Cleveland, OH


Albert Einstein College of Medicine University of Minnesota
Case Western Reserve University University of Missouri
Cornell University Medical Center University of New Mexico
Henry Ford Health System University of Pennsylvania
International Diabetes Center University of Pittsburgh
Joslin Diabetes Center University of South Florida
Massachusetts General Hospital University of Tennessee
Mayo Foundation University of Texas Southwestern University Medical Center
Medical University of South Carolina University of Toronto
Northwestern University University of Washington
University of California, San Diego University of Western Ontario
University of Iowa Vanderbilt University
University of Maryland School of Medicine Washington University, St. Louis
University of Michigan Yale University School of Medicine

        go to the top of this page

From the NIDDK
Undated webpage


Copyright ©

Go to the Copyright and Other Information page

This page was new at D-is-for-Diabetes on June 27, 2013

go to the top of this page go to home page read about us contact us read our disclaimer read our privacy policy search our website go to the site map find out what's new